منابع مشابه
Neurotrophins: A Ticket to Ride for BDNF
The secretion of BDNF from neurons is under activity-dependent control: this is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. New evidence shows that interaction between a motif in the tertiary structure of BDNF and the sorting receptor carboxypeptidase E directs this neurotrophin to the regulated secretory pathway.
متن کاملToxo has a ticket to ride
Lethal shock is subverted by crippling a family of G proteins in endothelial cells, according to Korhonen and colleagues on page 411. Bee stings or other allergens can cause anaphylactic shock in severely allergic individuals by triggering mast cell activation and the release of anaphylactic mediators like histamine and platelet activating factor (PAF). At high enough levels, these mediators ca...
متن کاملTicket to Ride: tRNA-Related Sequences and Systemic Movement of mRNAs.
Movement of macromolecules through the plant phloem provides a mechanism for long-distance signaling that plants use in development, disease resistance, and other adaptive responses (reviewed in Spiegelman et al., 2013). For example, full-length RNAs, such as the Arabidopsis thaliana GIBBERELLIC ACID INSENSITIVE, and potato (Solanum tuberosum) BEL5 mRNAs, and small RNAs, including numerous micr...
متن کاملTicket to
The start of the European Electronic Toll Service (EETS) appears far from being thoroughly realized, because of the unclear definition of a business model especially from the point of view of the EETS Providers. Toll Chargers started to approach EETS at a greater speed, as they shall accept any possible Provider from October 2012. The EETS Directive is one of the factors affecting the next arch...
متن کاملThe Ticket to Transport
Cell nuclei are like gated communities—quite selective about who gets in. And understandably so, because if the wrong proteins showed up at the wrong time and place, the consequences could be disastrous. The standard procedure for moving large molecules that cannot diffuse from the cytoplasm into the nucleus is to use the transport proteins known as karyopherins as escorts. How do karyopherins ...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2000
ISSN: 1471-0072,1471-0080
DOI: 10.1038/35043008